Prediction algorithm of the functional state of women with postmastectomy syndrome

According to many scientists, breast cancer and the associated postmastectomy syndrome, prolonged duration negatively to his notes on the functional state of the cardiovascular system [1; 2; 6–9], which attracts attention to itself by the rehabilitation. Evaluation of functional state has a crucial role in determining the capacity of women with postmastectomy syndrome to carry the load of different nature and can serve as a criterion for the efficiency of physical rehabilitation and the possibility of corrective training program.


Introduction
According to many scientists, breast cancer and the associated postmastectomy syndrome, prolonged duration negatively to his notes on the functional state of the cardiovascular system [1; 2; 6-9], which attracts attention to itself by the rehabilitation. Evaluation of functional state has a crucial role in determining the capacity of women with postmastectomy syndrome to carry the load of different nature and can serve as a criterion for the efficiency of physical rehabilitation and the possibility of corrective training program.
Despite the considerable amount of research devoted to the study of functional status of persons of different age groups [3][4][5], remains unexplored issues for its women with postmastectomy syndrome. In addition, it is important to take into account the integral index of the cardiovascular system, which fully characterize the level of its functional state.
The foregoing definitely indicates the importance of development a method of evaluating the functional state of the cardiovascular system of women with the postmastectomy syndrome to monitor the effectiveness and appropriateness of the applied rehabilitation.

Relationship with the academic programs, plans, themes
The selected research direction corresponds to the research topic of Lviv State University of Physical Culture "Basis of physical rehabilitation of women with the postmastectomy syndrome" (state registration 0115U007008).

The purpose of the research:
to create an algorithm for prediction of functional status of women with postmastectomy syndrome in terms of the cardiovascular system.

Tasks:
1. To prove the criteria of the functional state of women with postmastectomy syndrome.
2. To develop a method of evaluation of the functional state of the cardiovascular system in women with postmastectomy syndrome on the basis of objective consideration of its performance.
3. To determine levels of projected functional state of the cardiovascular system in points.

Material and Methods of the research
The article used the following methods: theoretical analysis of scientific and methodical literature, chest rheography, tonometry, methods of mathematical statistics.
The study was conducted on the basis of Zaporizhzhya Regional Oncology Center. The study involved 165 women with postmastectomy syndrome, who underwent a radical mastectomy for Madden, the average age was 60,27±0,79 years.

SLOBOZhANSKyI heRALD Of SCIeNCe AND SPORT
dition level (PCL) by the E. A. Pirogova, 1986 formula [5] and by building correlation matrix were selected multiple regression factors that correlated with the dependent variable (PCL) and explained its variation.
In the multiple regression model to assess the predictable level of the functional state (PLFS) were included those factors that were statistically significant correlation coefficients.
In particular, the following results were obtained calculating the parameters of the linear regression equation: The standard error was 0.03 and helped to determine the confidence interval for the estimated amount of functional state with a probability of 97%.
Thus it could be argued that obtained statistically significant regression equation (the hypothesis that the quantification of the connection between the dependent variable in the model and that it is essential to explain).
In this way, the calculated model of the predictable level of functional state is: where PLFS − predictable functional state of the cardiovascular system; To test the validity of the formula for calculating the estimated amount of the functional state of the cardiovascular system used results Ruf'e index, by determining the correlation coefficient between the actual value and its estimate calculated using regression equation.
As a result of checking the validity of the developed formula was obtained correlation coefficient r=-0,900, p<0,000, indicating that with increasing values predictable functional state decreased index Ruf'e or vice versa.

Conclusions
The proposed method allows a high degree of probability to assess the level and conduct rapid monitoring for the functional state of the cardiovascular system of women with postmastectomy syndrome and to determine the effectiveness of treatment, rehabilitation and make adjustments to the program of rehabilitation.
Prospects for further research include identifying features of the functional state of respiratory system of women with postmastectomy syndrome with different levels of the functional state of the cardiovascular system.