The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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Traditional Herbal Medicine for Dysfunctional Uterine Bleeding versus Western Medicine: A Systematic Review of Randomized Controlled Trials

기능성 자궁출혈에 대한 한약치료 : 체계적 문헌 고찰

  • Park, Eo-Jin (Dept. of Korean Medicine Obstetrics and Gynecology, Chung-Yeon Korean Medicine Hospital) ;
  • Jo, Hee-Geun (Chung-Yeon Medical Institute) ;
  • Choi, Ji-Hyun (Dept. of Obstetrics and Gynecology, Chosun University Hospital)
  • Received : 2018.09.19
  • Accepted : 2018.11.26
  • Published : 2018.11.30
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Abstract

Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine. Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.

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