Antioxidant Activities of Three Dihydrochalcone Glucosides from Leaves of Lithocarpus pachyphyllus

Wei-Min Yang; Ji-Kai Liu; Xiang-Dong Qin; Wan-Lin Wu; Zhi-He Chen

doi:10.1515/znc-2004-7-805

Open Access Published by De Gruyter June 2, 2014

Antioxidant Activities of Three Dihydrochalcone Glucosides from Leaves of Lithocarpus pachyphyllus

Wei-Min Yang , Ji-Kai Liu , Xiang-Dong Qin , Wan-Lin Wu and Zhi-He Chen

From the journal Zeitschrift für Naturforschung C

https://doi.org/10.1515/znc-2004-7-805

Abstract

In vitro antioxidant activities of three sweet dihydrochalcone glucosides from the leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae), trilobatin 2″-acetate (1), phloridzin (2) and trilobatin (3), were investigated. The IC₅₀ (50% inhibitory concentration) values for compounds 1-3 of lipid peroxidation in rat liver homogenate were 261, 28, 88 μm, respectively. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC₅₀ (50% effective concentration) values of 575, 167, 128 μm, and glutathione peroxidase (GSH-Px) activity with EC₅₀ values of 717, 347, 129 μm, respectively, and showed only weak DPPH (1,1- diphenyl-2-picrylhydrazyl) radical scavenging activity

Keywords: Antioxidant Activities; Lithocarpus pachyphyllus; Sweet Dihydrochalcone Glucosides

Received: 2003-12-9

Revised: 2004-1-15

Published Online: 2014-6-2

Published in Print: 2004-8-1

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antioxidant Activities of Three Dihydrochalcone Glucosides from Leaves of Lithocarpus pachyphyllus

Abstract

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