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Licensed Unlicensed Requires Authentication Published by De Gruyter June 2, 2011

Abnormalities of the penis in utero – hypospadias on fetal MRI

  • Stefan F. Nemec EMAIL logo , Gregor Kasprian , Peter C. Brugger , Dieter Bettelheim , Ursula Nemec , Christian R. Krestan , Siegfried Rotmensch , David L. Rimoin , John M. Graham and Daniela Prayer

Abstract

Objective: To demonstrate the visualization of penile abnormalities on fetal magnetic resonance imaging (MRI).

Methods: This retrospective study included five fetuses (25+0 to 31+6 gestational weeks) with penile abnormalities, positively depicted on fetal MRI, using prenatal ultrasonography (US) as a standard of reference. On MRI, the penis, as well as the scrotum and testicles, were evaluated. All fetal organs were reviewed to define penile abnormalities as isolated or in association with other anomalies. Furthermore, US and MRI findings were compared.

Results: Posterior hypospadias were demonstrated in all five fetuses, and abnormal testicular descent in two. Associated anomalies were present in all five fetuses on MRI, including abdominal/urogenital pathologies in four; brain pathologies in three; and craniofacial, cardiac, musculoskeletal, pathologies each in one fetus, and intrauterine growth retardation in one fetus. Compared to US, additional MRI findings were shown in four of five fetuses.

Conclusions: Our MRI results demonstrate the visualization of fetal penile abnormalities and associated pathologies, which may provide information for perinatal management. MRI may show additional findings compared to prenatal US in certain cases.


Corresponding author: Stefan Franz Nemec, MD Division of Neuroradiology and Musculoskeletal Radiology Department of Radiology Medical University Vienna Waehringer Guertel 18-20 A-1090 Vienna Austria Tel.: +431404004895 Fax: +431404004864

Received: 2010-11-5
Revised: 2011-1-8
Accepted: 2011-2-4
Published Online: 2011-06-02
Published Online: 2011-06-2
Published in Print: 2011-07-01

©2011 by Walter de Gruyter Berlin Boston

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