Assessing the quality of life of asthmatic children using the PedQLâ„¢

  • Yulia Wigoeno Department of Child Health, Medical School, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Rini Sekartini Department of Child Health, Medical School, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Darmawan Budi Setyanto Department of Child Health, Medical School, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Sri Rezeki Hadinegoro
Keywords: quality of life, children with asthma, prevalence

Abstract

Background Asthma is the most common chronic respiratory illness in childhood. Its prevalence in Indonesia is 6.7 - 10%. Asthma influences growth, development and quality of life in affected children. Studies abroad have shown that children with asthma have a decreased quality of life (QoL), yet such data is limited in Indonesia.
Objective To assess quality of life of asthmatic children in Indonesia, the influence of sociodemographic and medical characteristics on QoL, and to compare child self-reporting to their parents’ proxy-reporting.
Methods This descriptive analysis, cross-sectional study was conducted from May to July 2010. We assessed the quality of life of asthmatic children aged 2-18 years using the PedsQLTM 4.0 generic scale.
Results A total of 100 asthmatic children and their parents were included, with 43% of the subjects aged 8-12 years and a male to female ratio of 1.7:1. We observed that 26.8% of children who self-reported had impaired QoL, while 35% of children who reported by proxy had impaired QoL. In a multivariate analysis, we found the following characteristics to independently influence QoL: male gender (P 0.018 OR 0.26 95% CI 0.08 to 0.9) based on child self-report, and having partly controlled/uncontrolled asthma based on self-report and proxy-report (P 0.013 OR 6.24 95% CI 1.48 to 26.37 and P 0.018 OR 3.43 95% CI 1.24 to 10.05, respectively). There was good correlation between the self-report and the proxy-report on emotional and social functioning (r > 0.5), yet we found physical and school functioning to be weakly correlated (r < 0.5).
Conclusions We observed a relatively high (26.8-35%) impaired QoL in asthmatic patients. Parental assessment of their child’s QoL was generally lower than the child’s self-assessment. Male gender is a protective factor against impaired QoL, but having partly controlled/uncontrolled asthma is a risk factor for lower QoL. [Paediatr Indones. 2011;51:245-51].

References

1. Koenig JQ. Air pollution and asthma. J Allergy Clin Immunol. 1999;104:717-22.
2. O’Byrne P. GINA Workshop report update. c2004 [cited 2010 Jan 21]. Available from: http://www.ginaasthma.org
3. Epidemiologi asma. In: Rahajoe N, Supriyatno B, Setyanto DB, editors. Pedoman nasional asma anak. Jakarta: Pulmonologi Workgroup, Indonesian Pediatrician Association; 2004. p. 1-4.
4. Moonie SA, Sterling DA, Figgs L, Castro M. Asthma status and severity affect missed school days. J School Health. 2006;76:18-24.
5. Glazebrook C, McPherson AC, Mac-Donald IA, Swift JA, Ramsay C, Newbould R, et al. Asthma as a barrier to children’s physical activity: implications for body mass index and mental health. Pediatrics. 2006;118:2443-9.
6. Juniper EF. How important is quality of life in pediatric asthma? Pediatr Pulmonol Suppl. 1997;15:17-21.
7. Eiser C. Children’s quality of life measures. Arch Dis Child. 1997;77:350-4.
8. Seid M, Varni JW, Jacobs JR. Pediatric health-related quality-of-life measurement technology: intersections between science, managed care, and clinical care. J Clin Pscychol Med Settings. 2000;7:17-27.
9. Susanto Y. Penilaian kualitas hidup anak yang menderita kanker dengan metoda PedsQL [dissertation]. [Jakarta]: University of Indonesia, Medical school; 2009.
10. Sitaresmi MN, Mostert S, Gundy CM, Sutaryo, Vermaan AJP. Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia. Health Qual Life Outcomes. 2008;6:1-8.
11. MAPI Research TRUST. Pediatric quality of life inventory. [cited Jan 21 2010]. available from: http://www.mapi-trust.org
12. Diagnosis dan klasifikasi. In: Rahajoe N, Supriyatno B, Setyanto DB, editors. Pedoman nasional asma anak. Jakarta: Pulmonologi Workgroup, Indonesian Pediatrician Association; 2004. p. 12-5.
13. Fischer J, Corcoran K. Instrument for families. In: Fischer J, Corcoran K, editors. Measures for Clinical Practice and Research. 4 th ed. New York: Oxford University Press; 2007.
p. 239-40.
14. Bateman ED. Pocket guide for asthma management and prevention in children 5 years and younger. [updated 2009, cited Jan 21 2010]. Available from: http://www.ginaasthma.org
15. De Marco R, Locatelli F, Sunyer J, Burney P. Differences in incidence of reported asthma related to age in men and women: A retrospective analysis of the data of the European respiratory health survey. Am J Respir Crit Care Med. 2000;162:68-74.
16. Varni JW, Burwinkle TM, Rapoff MA, Kamps JI, Olson N. The PedsQLTM in pediatric asthma: reliability and validity of the Pediatric Quality of Life InventoryTM generic core scales and asthma module. J Behav Med. 2004;27:297-318.
17. Varni JW, Seid M, Skarr D, Burwinkle TM. Health Assessment Project—First Year Results, Data Insights Report No. 10 (Sacramento: Children’s Health Assessment Project). October 2000 [cited 2010 August 18]. Availble from: http://www.mrmib.ca.gov/MRMIB/HFP/PedsQLYr2CHHS.pdf
18. Suharto S. Faktor-faktor yang berhubungan dengan kualitas hidup anak asma [dissertation]. [Semarang]: Diponegoro University, Medical School; 2005.
19. Simon AE, Chan KS, Forrest CB. Assessment of children’s health-related quality of life in the United States with a multidimensional index. Pediatrics. 2008;121:e118-26.
20. Annet RD, Bender BG, DuHamel TR, Lapidus J. Factors influencing parent reports on quality of life for children with asthma. J Asthma. 2003;40:577-87.
21. Apter AJ, Reisine ST, Affleck G, Barrows E, ZuWallack RL. The influence of demographic and socioeconomic factors on health-related quality of life in asthma. J Allergy Clin Immunol. 1999;103:72-8.
22. Vila G, Hayder R, Bertrand C, Falissard B, Blic J, Simeoni MCM, et al. Psychopathology and quality of life for adolescents with asthma and their parents. Psychosomatics. 2003;44:319-28.
23. Warschburger P, Busch S, Bauer CP, Kiosz D, Stachow R, Petermann F. Health-related quality of life in children and adolescents with asthma: results from the ESTAR study. J Asthma. 2004;41:463-70.
24. Singh M, Mathew JL, Malhi P, Srinivas BR, Kumar L. Comparison of improvement in quality of life score with objective parameters of pulmonary function in Indian asthmatic children receiving inhaled corticosteroid therapy. Indian J Pediatr. 2004;41:1143-7.
25. Chen H, Gould MK, Blanc PD, Miller DP, Kamath TV, Lee JH, et al. Asthma control, severity, and quality of life: quantifying the effect of uncontrolled disease. J Allergy Clin Immunol. 2007;120:396-402.
26. Moy ML, Israel E, Weiss ST, Juniper EF, Dube L, Drazen JM, et al. Clinical predictors of health-related quality of life depend on asthma severity. Am J Respir Crit Care Med. 2001;163:924-9.
27. Sullivan SD, Wenzel SE, Bresnahan BW, Zheng B, Lee JH, Pritchard M, et al. Association of control and risk of severe asthma-related events in severe or difficult-to-treat asthma patients. Allergy. 2007;62:655-6.
28. Vollmer WM, Markson LE, O’Connor E, Frezier EA, Berger M, Buist AS. Association of asthma control with health care utilization: a prospective evaluation. Am J Respir Crit Care Med. 2002;165:195-9.
29. Parson SK, Barlow SE, Levy SL, Supran SE, Kaplan SH. Health related quality of life in pediatric bone marrow transplant survivors: according to whom? Int J Cancer Suppl. 1999;12:46-55.
30. Eiser C, Eiser JR, Stride CB. Quality of life in children newly diagnosed with cancer and their mothers. Health Qual Life Outcomes. 2005;3:29.
31. Herjanic B, Reich W. Development of a structured psychiatric interview for children: agreement between child and parent on individual symptoms. J Abnorm Child Psychol. 1982;10:307-24.
Published
2011-10-31
How to Cite
1.
Wigoeno Y, Sekartini R, Setyanto D, Hadinegoro S. Assessing the quality of life of asthmatic children using the PedQLâ„¢. PI [Internet]. 31Oct.2011 [cited 20Apr.2024];51(5):245-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/504
Received 2016-09-08
Accepted 2016-09-08
Published 2011-10-31