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Bioabatement to remove inhibitors from biomass-derived sugar hydrolysates

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Abstract

Bioabatement is a potential method to remove inhibitory compounds from lignocellulose hydrolysates that could be incorporated into a scheme for fermentation of ethanol from cellulose. Coniochaeta ligniaria NRRL30616, an Ascomycete that metabolizes furfural and 5-hydroxymethylfurfural, is a unique strain that may be useful for detoxifying biomass sugars. NRRL30616 and 23 related fungal strains were screened for the ability to metabolize furans and grow in dilute-acid hydrolysate of corn stover. NRRL30616 was the best strain for removal of inhibitors from hydrolysate, and abatement of hydrolysate by inoculation with the strain allowed subsequent yeast fermentation of cellulose to ethanol.

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Authors and Affiliations

  1. Fermentation Biotechnology Research Unit, NCAUR, USDA-ARS, 1815 N. University Street, 61604, Peoria, IL

    Nancy N. Nichols & Bruce S. Dien

  2. Departamento de Biología Aplicada, CITE II-B. La Cañada de San Urbano, University of Almeria, 04120, Almeria, Spain

    Gema M. Guisado & Maria J. López

Authors
  1. Nancy N. Nichols
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  2. Bruce S. Dien
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  3. Gema M. Guisado
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  4. Maria J. López
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Corresponding author

Correspondence to Nancy N. Nichols.

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Mention of trade names or commercial products in this article is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the U.S. Department of Agriculture.

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Nichols, N.N., Dien, B.S., Guisado, G.M. et al. Bioabatement to remove inhibitors from biomass-derived sugar hydrolysates. Appl Biochem Biotechnol 121, 379–390 (2005). https://doi.org/10.1385/ABAB:121:1-3:0379

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  • DOI: https://doi.org/10.1385/ABAB:121:1-3:0379

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