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Solid Tumor DNA Content Analysis

  • Protocol
Flow Cytometry Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 263))

Abstract

Flow cytometric DNA content analysis provides a rapid and reliable analysis of DNA ploidy and the proliferative fraction of tumor specimens. Both archival and fresh specimens are suitable for this technique. This information can be used in conjunction with traditional prognostic factors in the biological assessment of certain carcinomas. Among these tumors are early stages of breast, colon, lung, and bladder carcinomas.

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Author information

Authors and Affiliations

  1. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX

    Adel K. El-Naggar

  2. Service de Cytopathologie et Cytométrie Clinique, Institut Curie, Paris, France

    Philippe Vielh

Authors
  1. Adel K. El-Naggar
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  2. Philippe Vielh
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Editor information

Editors and Affiliations

  1. American Red Cross, Rockville, MD

    Teresa S. Hawley  & Robert G. Hawley  & 

  2. The George Washington University, Washington, DC

    Robert G. Hawley

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© 2004 Humana Press Inc.

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El-Naggar, A.K., Vielh, P. (2004). Solid Tumor DNA Content Analysis. In: Hawley, T.S., Hawley, R.G. (eds) Flow Cytometry Protocols. Methods in Molecular Biology™, vol 263. Humana Press. https://doi.org/10.1385/1-59259-773-4:355

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  • DOI: https://doi.org/10.1385/1-59259-773-4:355

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-234-6

  • Online ISBN: 978-1-59259-773-4

  • eBook Packages: Springer Protocols

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