Abstract
Malondialdehyde (MDA) and superoxide dismutase (SOD) in lens and plasma of patients with age-related and myopic cataract were assessed. Higher levels of lens MDA in myopic patients showed a greater lipid peroxidation process than in patients with age-related cataract indicating higher oxidative stress in myopic lens. The difference in plasma MDA of myopic cataract and age-related cataract patients was not significant. The SOD level was lower in myopic patients than in patients with age-related cataract.
Similar content being viewed by others
References
Mohan M. Study design and data of WHO-NPCB blindness survey—1986–1988. In: Lim ASM ed World's Major Blinding Conditions, Singapore: XXVI International Congress of Ophthalmology, 1990;182–187.
Green K. Free radicals and aging of anterior segment tissues of the eye: a hypothesis. Ophthalmic Res 1995;27(Suppl 1):143–149.
Zigler JS Jr, Goosey JD. Singlet oxygen as a possible factor in human senile cataract development. Curr Eye Res 1984;3:59–65.
Zigman S, Schultz JB, Schultz M. Measurement of oxygen production by in vitro human and animal lenses with an O2 electrode. Curr Eye Res 1998;17:115–119.
Author information
Authors and Affiliations
Corresponding author
Additional information
The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors also do not discuss the use of off-label products, which includes unlabeled, unapproved, or investigative products or devices.
Rights and permissions
About this article
Cite this article
Bhatia, R.P., Rai, R. & Rao, G.R.K. Role of malondialdehyde and superoxide dismutase in cataractogenesis. Ann Ophthalmol 38, 103–106 (2006). https://doi.org/10.1385/AO:38:2:103
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1385/AO:38:2:103