The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing
Fig 8
ES-62 acts to normalise the gut microbiome in HCD-fed mice.
The composition of bacterial phyla in gut (ileum plus colon) faecal matter (a) of male and female chow- (d56 and d340) and HCD- (PBS- or ES-62-treated; d340) mice presenting proportion values as pie charts using pooled samples to represent each cohort. The Bacteroidetes:Firmicutes ratio (b, c) and levels of Desulfovibrionaceae (d) and Enterobacteriaceae (e) present in gut faecal (ileum plus colon) matter of male (b, d, e) and female (c, d, e) chow- and HCD- (PBS or ES-62-treated) mice (each determined as proportion values) using pooled samples to represent each cohort at the indicated time-points are shown.