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Alterations in cellular expression in EBV infected epithelial cell lines and tumors

Fig 4

Hierarchical clustering heat map of gene expression of all samples and analysis of genes in distinct areas.

(A) Hierarchical clustering heat map of gene expression vs hg19 and the associated genes. Red denotes upregulation and blue denotes downregulation. The samples are identified by pathology (gastric and NPC), Tissue (gastric tumor, cell line, NPC tumor), Type (sc tumor, ip tumor, cell line), virus (EBV negative and EBV positive), and sample grouping (EBV negative vs EBV positive). Genes from the five distinct areas are listed. (B) IPA analysis for canonical pathways, upstream regulators, and disease and functions of the genes from Section 1. Genes that are upregulated in the gastric samples relative to the NPC.

Fig 4

doi: https://doi.org/10.1371/journal.ppat.1008071.g004