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RNA virus building blocks—miRNAs not included

Fig 1

Depiction of viruses for which small-RNA populations have been sequenced in an attempt to identify putative miRNAs.

Viruses are plotted based on confirmed miRNA numbers (left axis) versus both their life cycle (latent or nonlatent, right axis) and their overall genomic size (x-axis). ND denotes no miRNAs detected. DNA viruses (blue) include the following: BKPyV, JCPyV, MCPyV, VACV, RhCMV, HvAV, WSSV, HCMV, MDV, KSHV, HSV-1/-2, and EBV. Retroviruses (black) include the following: HIV, BLV, and SFV. RNA viruses (red) include the following: YFV, SINV, HCV, VSV, and IAV. BKPyV, BK polyomavirus; BLV, bovine leukemia virus; EBV, Epstein–Barr virus; HCMV, human cytomegalovirus; HCV, hepatitis C virus; HIV, human immunodeficiency virus; HSV-1/-2, herpes simplex virus-1/-2; HvAV, Heliothis virescens ascovirus; IAV, influenza A virus; JCPyV, JC polyomavirus; KSHV, Kaposi sarcoma-associated herpes virus; MCPyV, Merkel cell polyomavirus; MDV, Marek disease virus; miRNA, micro-RNA; RhCMV, Rhesus cytomegalovirus; SFV, simian foamy virus; SINV, Sindbis virus; VACV, vaccinia virus; VSV, vesicular stomatitis virus; WSSV, white spot syndrome virus; YFV; yellow fever virus.

Fig 1

doi: https://doi.org/10.1371/journal.ppat.1006963.g001