Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury
Fig 2
STAT6 signaling in bone marrow-derived cells is essential for parasite growth.
B6.SJL and STAT6-/- mice were reconstituted with bone marrow cells from B6.SJL or STAT6-/- mice for eight weeks, then infected by IV injection of 25,000 NBL. Areas of larvae were estimated, 13 days post injection. Each data set was collected from two experiments with similar results. n = 4 mice. Significant differences were determined by ANOVA and Tukey’s test. ***p < 0.0001.