Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains
Figure 3
Correlation between protection, viral titers and Wolbachia density.
Dots indicate mean value of the traits for each Wolbachia strain. Error bars are standard errors. Solid lines show predicted values from linear regressions for illustrative purposes. rg is the genetic correlation between traits. (A) Correlation of survival between DCV- and FHV-infected flies (negative natural log of hazard ratios). (B) Correlation between DCV and FHV titers. (C–D) Correlation between viral titer and survival following (C) DCV infection or (D) FHV infection. Viral titers were estimated as viral RNA concentrations relative to the Drosophila gene EF1α100E. (E–F) Relationship between Wolbachia density and survival in (E) DCV- and (F) FHV-infected flies. Wolbachia density was estimated as the ratio between copy numbers ofthe Wolbachia gene atpD and the Drosophila gene Actin 5C.