Kinetics of Myeloid Dendritic Cell Trafficking and Activation: Impact on Progressive, Nonprogressive and Controlled SIV Infections
Figure 12
Increased post-SIVagmSab infection production of proinflammatory cytokines by intestinal unstimulated mDCs occurs only in progressive infection.
Percentages of intestinal unstimulated mDCs producing TNF-α in (a) PTMs, (b) AGMs and (c) RMs prior to and during acute and chronic SIVagmSab infection. Percentages of intestinal unstimulated mDCs producing IL-6 in (d) PTMs, (e) AGMs and (f) RMs prior to and during acute and chronic SIVagmSab infection. Gating was done on live cells and then on Lineageneg HLA-DRpos CD11cpos.