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Immunization against a Saccharide Epitope Accelerates Clearance of Experimental Gonococcal Infection

Figure 1

Simplified schematic of the oligosaccharide (OS) structure of gonococcal LOS.

Lipooligosaccharide glycosyl transferase (lgt) genes that are involved in LOS biosynthesis and are subject to phase variation are indicated in grey italic font. Each transferase catalyzes the substitution of the next more distal hexose onto the LOS backbone. The grey shaded box represents the minimum OS structure expressed by naturally occurring gonococcal strains that is required for mAb 2C7 binding.

Figure 1

doi: https://doi.org/10.1371/journal.ppat.1003559.g001