Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin
Figure 5
Nasal colonisation of S. aureus in the FVB wild-type and Lor−/− mouse.
Mice were inoculated intra-nasally with S. aureus Newman (2×108 CFU). Mice were euthanized and bacterial burden in the noses established on days 1, 3, 10 and 21. Results expressed as mean Log CFU per nose (n = 15, per group). Statistical analysis was performed using the Mann-Whitney test.