Comparative Pathogenomics Reveals Horizontally Acquired Novel Virulence Genes in Fungi Infecting Cereal Hosts
Figure 1
Alignment between F. graminearum and F. pseudograminearum.
F. graminearum chromosomes are ordered in decreasing size. (A) Dot-plot representing a whole genome alignment between F. graminearum isolate Ph1 and F. pseudograminearum isolate CS3096. The alignment was generated with NUCmer, part of the MUMmer 3 comparative sequence analysis package. Sequences were pre-masked for known repetitive elements and simple repeats using RepeatMasker. The dot plot represents the best 1∶1 alignment between the two genomes. Dots closest to the diagonal represent co-linearity between the two genomes. Red represents matches in the forward direction and blue is indicative of inversions in part of the mapped contig relative to the F. graminearum genome. (B) Distribution of gaps in the alignment between F. pseudograminearum and F. graminearum, relative to the F. graminearum genome. F. graminearum chromosomes were divided into 100 Kbp non-overlapping windows and the unaligned nucleotides in each window summed and expressed as a percentage.