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Autophagy Protein Atg3 is Essential for Maintaining Mitochondrial Integrity and for Normal Intracellular Development of Toxoplasma gondii Tachyzoites

Figure 11

Altered mitochondrial ultrastructure in TgAtg3-depleted tachyzoites observed by electron microscopy.

Ultrathin section of a TgAtg3-depleted (3 days of ATc treatment) tachyzoite showing the dramatic alteration of the mitochondrion, where cristae remnants are still visible (arrows), but which is filled up with membranous profiles (arrowheads), whereas Golgi (G), apicoplast (A), rhoptries (R) and dense granule (D) look normal.

Figure 11

doi: https://doi.org/10.1371/journal.ppat.1002416.g011