Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting
Figure 8
vRNPs (light gray) complexed with M1 (blue) and NEP (red) associate with dense chromatin in proximity to Rcc1 (orange). During or immediately after generation of RanGTP (purple), the proximity of vRNPs to Rcc1 may allow vRNPs access to a RanGTP-Crm1 complex before it can diffuse to other sites in the nucleus.