Crystallography of a Lewis-Binding Norovirus, Elucidation of Strain-Specificity to the Polymorphic Human Histo-Blood Group Antigens
Figure 3
Overall structure of VA207 P protein monomer and comparison of VA207 and VA387 P dimers complexed with oligosaccharides.
(A) Ribbon representation of VA207 P monomer shown in cyan. Secondary structural elements are labeled as in Figure 2. (B) Superimposition of the P dimer structures of VA207 (cyan) with Lewis Y tetrasaccharide (Ley-tetra) and VA387 (purple; PDB entry: 2OBT) with B trisaccharide (B-tri) in stereo view. The major structural differences in the loop region of P2 subdomain between the two strains are indicated in yellow.