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High Expression of CD244 and SAP Regulated CD8+ T Cell Responses of Patients with HTLV-I Associated Neurologic Disease

Figure 1

Expression of CD244 on CD8+ T cells of HTLV-I-infected patients.

(A) Representative histograms of CD244 expression on CD8+ T cells of a ND, an AC and a patient with HAM/TSP. Staining in ND (opened histogram), AC (grayed histogram) and patient with HAM/TSP (closed histogram) were shown. (B) Comparison of CD244 expression in CD8+ T cells of NDs and HTLV-I-infected patients. The data were obtained from 14 NDs, 8 ACs and 13 patients with HAM/TSP. The horizontal line represents the median. (C) CD244 expression on antigen-specific CTLs. CD244 expressions were shown in Tax11-19- specific and CMVpp65-specific CD8+ T cells of a patient with HAM/TSP.

Figure 1

doi: https://doi.org/10.1371/journal.ppat.1000682.g001