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Quantitative Models of In Vitro Bacteriophage–Host Dynamics and Their Application to Phage Therapy

Figure 1

Phage decay in the culture medium in the absence of hosts.

The plot shows data from one of the three cultures in the phage decay experiment, with observed concentrations in log10 PFU mL−1 (points) and the fitted curve log10 V(t) = log10 V0mt (line). The phage concentration declines linearly on log-linear axes, indicating approximately exponential decay with estimated rate 1.062×10−2 h−1.

Figure 1

doi: https://doi.org/10.1371/journal.ppat.1000253.g001