Chronic HIV-1 Infection Frequently Fails to Protect against Superinfection
Figure 6
Case 4 (QD022): Intersubtype Superinfection (Subtype A–C) between 1,832 and 1,957 DPI Detected in env
The layout of this figure is similar to that of Figure 3, as described in the legend for Figure 3.
(A) Plot of viral load (log RNA copies/mL plasma) versus DPI with the number of sequences of each strain indicated.
B) Maximum-likelihood tree of env sequences from all time points. Cluster A contains sequences from 51, 522, and 1,832 DPI, while cluster C contains sequences from 1,957 and 2,752 DPI.
(C) Amplification of 50 env HIV-1 genome copies from the indicated time points using strain-specific primers (top panel) and common primers (bottom panel).
(D) Summary of the strains detected. Light gray = subtype A; black = subtype C.