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Effects of lifelong spontaneous exercise on skeletal muscle and angiogenesis in super-aged mice

Fig 7

Inhibitory effect of LSE on the reduction of angiogenic capacity confirmed by ex vivo aortic ring assay.

(A) 10Ⅹ magnification microscopic images of aortic ring assay. (B) Comparison of the number of sprouts extending after culture of isolated mouse aorta. All data are presented as the mean ± SD vs. control group of same age, ***p < 0.001 and ****p < 0.0001; vs. control group of different age, p < 0.0001.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0263457.g007