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Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities

Fig 4

Impaired locomotor activity among female Mecp2+/− rats during both light and dark phases at 16 and 23 weeks of age.

Bar graphs are mean ± SE (n = 6 rats per genotype). *p < 0.05, and **p < 0.01 vs. age-matched female Mecp2+/+ rats (Kruskal–Wallis with Dunn’s post hoc multiple comparisons test).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0258830.g004