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Circulating microparticles and activated platelets as novel prognostic biomarkers in COVID-19; relation to cancer

Fig 1

Flow cytometry gating strategy of microparticles (MPs).

A: The MPs were identified in a forward/side scatter histogram (R1) using calibrated beads. B: The expression of annexin V was then assessed within the defined MP population, and the annexin V-positive MPs (total MPs) were quantified (R2). C & D: Total MPs were further analyzedfor the expression of CD41, CD45, and CD146 to detect the platelet MPs (CD41+ MPs) and the endothelial derived MPs (CD45-CD146+ MPs).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0246806.g001