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Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes

Fig 7

Analysis of CD44+/CD22- stem cell population in theviable percentage of DU145 and PC3 cells.

A, B. Mean fluorescence intensity of CD44+ and CD24+ cell populations in DU145 and PC3 comparing total and viable populations using Annexin V/PI assay. The values repres ent the mean ± SD (n = 6). *** p < 0.001, **** p ≤ 0.0001, significantly different from total vs viable. ## p ≤ 0.001, # p ≤ 0.0001, significantly different from the total population control. %% p ≤ 0.001, % p ≤ 0.0001, significantly different from the viable supopulation control.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0246733.g007