The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies
Fig 3
Xenograft models in the SRG rat and NSG mouse.
A) Tumor growth curve in NSG mice and SRG rats inoculated with 2x106 HCT-116 cells subcutaneously in the hind flank. Tumor width and length were measured three times weekly to calculate volume. B) Tumor growth curve in SRG rats inoculated with 5 x106 MIA-PaCa-2 cells. C) Tumor growth curve in SRG rats inoculated with 5 x106 HCC1954 cells. D) Tumor growth curve in SRG rats inoculated with 10 x106 786-O cells.