Combining signal and sequence to detect RNA polymerase initiation in ATAC-seq data
Fig 7
Distribution of nascent transcription reads for classification results.
Distribution of mapped reads from nascent transcription SRRs, for OCRs corresponding to the training set (green histograms, top) and each classification metric (blue histograms, metric noted in upper right corner of each panel). Note the difference in scales among plots, to better appreciate the distribution of coverage in each scenario. The leftmost bin in the “positive”, “TP”, and “NF” panels correspond to very low levels of nascent transcription rather than no transcription, which are generally associated to regulatory regions.