Creatine kinase rate constant in the human heart at 7T with 1D-ISIS/2D CSI localization
Fig 5
Skeletal muscle kf determined by conventional saturation transfer approach and approach with 1D-ISIS/1D-CSI localization.
(A) MR image of calf muscle showing the locations of the 1D-CSI voxels. (B) Series of spectra for conventional saturation transfer approach. The peak localization are as α-ATP at -7.6 ppm, γ-ATP at -2.5 ppm, PCr at 0.0 ppm, phosphodiester (PDE) at 3.2 ppm and inorganic phosphates (Pi) at 5.2 ppm. γ-ATP peak is visible in the top spectrum and is selectively saturated for other spectra. Saturation time was progressively increased and PCr peak intensity decreases with the increasing duration of saturation of γ-ATP. (C) Stack of spectra showing Mc (without ATP saturation, right) and Ms (with ATP saturation, left) using method.