Unexpected differences in the pharmacokinetics of N-acetyl-DL-leucine enantiomers after oral dosing and their clinical relevance
Fig 1
Chemical structure of N-acetyl-leucine.
(a) Stereochemistry of the enantiomers. (b) Amide resonance structures showing similarity to an imine. Extending from the tetrahedral chiral carbon is a solid wedge to indicate a bond projecting above the plane of the paper and a hashed wedge to indicate a bond projecting below the plane of the paper.