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Molecular mechanisms involved in drug-induced liver injury caused by urate-lowering Chinese herbs: A network pharmacology study and biology experiments

Fig 3

Distribution and the bubble map of core pathways.

Note: (A.) The vertical axis is the path name and the horizontal axis is the Rich Factor value. The larger the P-value, the higher the channel enrichment; the size of the point indicates the number of enriched targets; the color of the dots is red to green. The value is from small to large. (B.) The yellow to brown pathway lines represent the pathways for important target enrichment, from yellow to brown indicating that the pathway P-values are small to large.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0216948.g003