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Recurrent chromosomal and epigenetic alterations in oral squamous cell carcinoma and its putative premalignant condition oral lichen planus

Fig 5

DNA methylation values of loci assumed to be hypermethylated in both oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC) as compared to normal controls.

Methylation gained from normal control to OLP (A), loci exclusively hypermethylated in oral squamous cell carcinoma (OSCC) (gaining methylation in OSCC; B) and loci continuously losing DNA methylation from controls via OLP to OSCC (C). Different colors of lines indicate individual CpG loci.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0215055.g005