Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway
Fig 6
α-defensin cytotoxic activity toward adult TM.
Cytotoxic activity of reduced α-defensins on adult TM males and females (obtained from female IL-4Rα KO mice on day 116 of infection) was measured by lactate dehydrogenase release assay. Data are mean ± SD (n = 6 each, and α -defensin 4: n = 5 adult worms) from 1 experiment. Statistical significance was computed by the Mann-Whitney test.