Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme
Fig 2
Median joining networks of all available strain sequences for TP0136, TP0462, TP0548, TP0705 and TP0865.
Alleles found in 120 clinical samples examined in this study (samples from France and Switzerland) and in 63 samples published in [24, 25, 36] (total n = 183) are shown. Median joining networks per locus show the different allelic variants and the number of mutational differences among them. Number of mutations, when above one, is given close to branches. Red branch indicates the mutation that did not result in amino acid replacements. Inferred allelic variants (median vectors) are shown as black connecting dots. If contiguous, indels were considered as a single event only. Yellow circles represent the SS14-clade and brown circles represents the Nichols-clade. The number found among the 183 samples is shown inside the circles. Allelic variant numbering as proposed for the MLST scheme are shown in the grey fields.