A stable isotope dilution tandem mass spectrometry method of major kavalactones and its applications
Fig 2
Targeted UPLC-MS/MS analysis of DHM in mouse liver tissues.
Reconstructed ion chromatograms of DHM in liver tissues from mice with no kava (A), 1.5 h (B) and 24 h (C) after kava administration. (D) Mass spectra of DHM and [2H2]-DHM (the internal standard). The mass extraction window was of ± 5 ppm. The scale of the signal of panel C was normalized to the response of DHM in panel B.