Tetracyclines function as dual-action light-activated antibiotics
Fig 8
MIC determination in light and dark.
(A) Initially we tested whether both DMCT and DOTC could be activated with BL. Next a standard broth microdilution assay (16 h) was conducted with incubation either in dark or exposed to 0.5 J/cm2 BL. Three examples are given. (B) MRSA with DOTC; (C) E. coli (5–66 resistant) with DMCT; (D) E. coli (UTI 89) with MC.