Doxorubicin chemotherapy affects the intracellular and interstitial free amino acid pools in skeletal muscle
Fig 3
Schematic representation of the experimental groups and experimental procedures.
(A) Representation of the experimental groups receiving an injection of 1.5 mg/kg dose (groups 1–8) or 4.5 mg/kg (groups 9–16) of DOX administered i.p. A sham injection is administered to the control group (Ctrl). (B) Representation of the experimental proceedings for dialysate, blood and tissue collection following microdialysis probe insertion and carotid artery cannulation.