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p53 is required for brain growth but is dispensable for resistance to nutrient restriction during Drosophila larval development

Fig 5

Energy storage is not affected in p53 mutant larvae under nutrient restriction.

(A) Graph showing total TAG quantification of wild-type (w1118, “n” is 3) and p53 null (p53-ns, “n” is 3) larvae under Fed or NR conditions. (B) Graph showing total glycogen quantification of wild-type (w1118, “n” is 3) and p53 null (p53-ns and p535A-1-4 alleles, “n” is 3) larvae under Fed or NR conditions. (C) Graph showing total protein quantification of wild-type (w1118, “n” is 3) and p53 null (p53-ns and p535A-1-4 alleles, “n” is 3) larvae under Fed or NR conditions. One-way ANOVA and Tukey post-test statistical tests were used. *, ** and **** means p-value < 0.05, <0.01 and <0.001 respectively.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0194344.g005