5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα
Fig 4
Effects of 5-ASA intervention on inflammation and tight junction of the small intestine.
(A) qPCR analysis of small intestinal lysates for gene expression of PPARγ, IL-6, Mrc1, Ym1 and MCP1. (B) qPCR analysis of small intestinal lysates for gene expression of ZO-1. Data are presented as means ± SEM, n = 9–10 mice, aP < 0.05 vs. HFC, bP < 0.01 vs. HFC, cP < 0.001 vs. HFC.