Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients
Fig 1
Risk allele frequency of associated NAT2 variants by DILI grade.
The frequencies of the risk variants (rs1041983 A, rs1495741 A and NAT2 SA) increase with DILI grade. There was only 1 patient with grade 4 DILI, who was homozygous for the non-risk variants. DILI: drug-induced liver injury, SA: slow acetylators.