Crystal digital droplet PCR for detection and quantification of circulating EGFR sensitizing and resistance mutations in advanced non-small cell lung cancer
Fig 4
Monitoring of targeted sensitizing and resistance EGFR mutations and circulating cell-free DNA levels over time in 6 metastatic NSCLC patients using dPCR.
Coloured region indicates period of chemotherapy. Radiological assessment of patient response is indicated above the figures. Empty circles and squares indicates sensitizing and resistance mutations positives by dPCR but not detected by NGS respectively.