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Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes

Fig 5

Splenic sympathetic innervation regulates CXCL13 expression.

Spleen from control mice or mice subjected to chemical sympathectomy by 6-OHDA administration were assessed for expression of TH and CXCL13 by confocal microscopy (A) and quantified (B). Expression of Th, Ccl19, Ccl21 and Cxcl13 expression by qRT-PCR. *P<0.05, *** P<0.001.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0182416.g005