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Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering

Fig 5

Metabolites of S. kanamyceticus CG305 and its recombinant overexpressing strains.

(a) HPLC analysis of metabolites. (b) Analysis of secondary metabolite yields. (c) Stability of kanamycin B yields from S. kanamyceticus JKE1, JKE2, JKE3, and JKE4.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0181971.g005