Real-time computed tomography fluoroscopy-guided solitary lung tumor model in a rabbit
Fig 4
Results of lung cancer model in rabbit on positron emission tomography/computed tomography (PET/CT) scan, necropsy, and H&E staining.
(A) Tumor images on PET/CT scan. (B) Tumor formation on necropsy. (C) Microscopic findings on H&E staining (×50). In group 1, tumors are detected in the thoracic wall on PET/CT and necropsy. In group 2, multiple tumor lesions are shown in the lung parenchyma, pleural cavity, and thoracic wall on PET/CT with necropsy. In group 3, hypermetabolic lesions are shown only in lung parenchyma and mild hyper-metabolism is adjacently detected to pleural cavity on PET/CT. Multiple tumor lesions are identified in the lung and plural cavity on necropsy. Solitary lung cancer models in rabbit were developed in group 4. The white arrow indicates the VX2 carcinoma lesion. Microscopic findings of tumor cell (T) and alveolar epithelial cell (E).