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Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina

Fig 5

Suppression of nuclei ATF4 in Müller glial cells by bilberry extract.

(a-d) Co-immunostaining for ATF4 (green) and glutamine synthetase (red), a marker for Müller glial cell, 12 h after light exposure. ATF4 staining was observed in the nuclei (DAPI, blue) of Müller glial cells after light exposure; however, this translocation was suppressed by bilberry extract (c) or NAC (d). n = 5/ group. Scale bar, 10 μm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0178627.g005