p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging
Fig 7
Only the in vivo animal model with a long-term p38α deficiency drives to inactivation of HSP27.
Wild type and p38α knock out livers of all groups of age were Western blotted for p-HSP27 (Ser82) and total HSP27. α-tubulin was used as a loading control. Data are shown as mean ± SD. *P < 0.05 WT versus KO; $ $P < 0.01 old versus adult.