Influence of Biodentine® - A Dentine Substitute - On Collagen Type I Synthesis in Pulp Fibroblasts In Vitro
Fig 7
Biodentine® suspensions decreased the collagen type I and TGF-β1 concentration.
Collagen type I (A) and TGF-β1 (B) concentrations were measured by quantifying the fluorescence intensities of the respective immunhistochemical stainings of cultures treated with Biodentine® suspensions of low (dotted bar), moderate (striped bar) or high (bricked bar) Biodentine® concentrations in comparison to control cultures (white bar). The data displayed are representative of two independent experiments performed with comparable results. Average fluorescence intensity per cell (mean ± SD) from 14 to 17 individual cells per experimental condition were calculated. * p ≤ 0.05; *** p ≤ 0.001.