Reentry and Ectopic Pacemakers Emerge in a Three-Dimensional Model for a Slab of Cardiac Tissue with Diffuse Microfibrosis near the Percolation Threshold
Fig 8
Electrograms at different locations in the tissue during reentry.
The signals of different electrodes are plotted in arbitrary units for a numerical simulation showing reentry. Four snapshot of the top view of the tissue slab for times t = 16.5 ms, t = 500 ms, t = 1000 ms, and t = 1500 ms. The location of the electrodes is shown in the first snapshot by white circles. The electrodes are located at 0.01 cm from the slab of tissue. Signals calculated in each electrode, following Eq (6), are plotted. Black and red curves correspond to electrodes inside and outside of the fibrotic region, respectively. Note that vertical axis scale is modified for panels C-E due to the weak signal inside the fibrotic area. Parameter values: ϕ = 0.72, , system size is 7 × 7 × 0.01 cm3 (N = 10 layers), Ro = 1.4 cm, and total time of simulation t = 1500 ms.