Delivery of Human Adipose Stem Cells Spheroids into Lockyballs
Fig 1
Fabrication, material properties and the in vitro behavior of lockyballs.
(A, B, C) Sequential steps of layer-by-layer fabrication of lockyball using two-photon polymerization from photosensitive biomaterial. (D) Scanning electron microscopy image of a fabricated lockyball. (E) Representative results of estimation of lockyball stress-strain relationship using compression test performed with MicroSquisher® (CellScale, Canada). The stress-strain relationship is typical of solid polymers. (F) Interlocked lockyballs demonstrating two types of interlocking mechanisms: hook-to-hook and hook-to-loop (arrows). Phase contrast. Details of both types of interlocking mechanisms are illustrated in inserts on the right side of image. Bars size: 100 micrometers.